www.rethinkpbc.com Review:



RethinkPBC | Intercept Pharmaceuticals, Inc. - Learn how, after more than 20 years, new research and development is changing the landscape of primary biliary cirrhosis (PBC) with potential for new therapy options.

  • http://www.rethinkpbc.com/pbc-overview/clinical-history/ Clinical history | RethinkPBC.com - For more than 150 years, PBC has been recognized and treated, but since 1989, the standard of care has remained the same.
  • http://www.rethinkpbc.com/pbc-overview/pathophysiology/ Pathophysiology | RethinkPBC.com - The pathophysiology of PBC is complex, with both genetic and environmental components leading to bile duct damage.
  • http://www.rethinkpbc.com/diagnosing-pbc/genetics/ Genetics of PBC | RethinkPBC.com - First-degree relatives of patients with PBC are at significantly higher risk for this disease and should strongly consider getting screened.
  • http://www.rethinkpbc.com/pbc-overview/natural-history/ Natural history | RethinkPBC.com - Since the use of the standard of care UDCA has become more widespread, the natural history of primary biliary cirrhosis has taken a turn for the better.
  • http://www.rethinkpbc.com/pbc-overview/potential-complications/ Potential complications | RethinkPBC.com - A variety of serious short- and long-term complications may require monitoring and management during the course of PBC.
  • http://www.rethinkpbc.com/diagnosing-pbc/testing/ Testing for PBC | RethinkPBC.com - Per AASLD and EASL guidelines, establishing a diagnosis of PBC is generally based on elevated ALP and AMA levels.
  • http://www.rethinkpbc.com/diagnosing-pbc/concomitant-autoimmune-diseases/ Concomitant autoimmune diseases | RethinkPBC.com - PBC has an increased association with concomitant autoimmune diseases such as rheumatoid arthritis, autoimmune thyroid disease, and Sjogren syndrome.
  • http://www.rethinkpbc.com/pbc-biochemical-markers/alp/ ALP | RethinkPBC.com - Elevated alkaline phosphatase (ALP) is a key marker in diagnosis and monitoring of PBC.
  • http://www.rethinkpbc.com/pbc-biochemical-markers/bilirubin/ Bilirubin | RethinkPBC.com - Bilirubin, like ALP, is an essential prognostic marker in PBC (as shown in the Lammers 2014 analysis).
  • http://www.rethinkpbc.com/managing-pbc/early-intervention-in-pbc/ Early intervention in PBC | RethinkPBC.com - When a patient is diagnosed with PBC, therapy with standard of care UDCA should be started as soon as possible.
  • http://www.rethinkpbc.com/managing-pbc/biochemical-response/ Biochemical response | RethinkPBC.com - Patients with PBC who have a biochemical response to UDCA have significantly better outcomes than inadequate responders, who may need alternative therapy.
  • http://www.rethinkpbc.com/managing-pbc/monitoring-alp/ Monitoring ALP | RethinkPBC.com - Current data reinforce the importance of closely monitoring ALP to aid in managing PBC.
  • http://www.rethinkpbc.com/managing-pbc/liver-transplant/ Liver transplant | LivingwithPBC.com - Cirrhosis and liver failure make PBC one of the top 10 causes of liver transplant in the US for untreated patients and for patients who do not respond to UDCA.
  • http://www.rethinkpbc.com/pbc-symptom-management/pruritus/ Pruritus | RethinkPBC.com - Almost two-thirds of patients with PBC may experience pruritus during the course of their disease, requiring vigilant monitoring.
  • http://www.rethinkpbc.com/pbc-symptom-management/fatigue/ Fatigue | RethinkPBC.com - The fatigue that patients experience because of PBC can have serious consequences including associated depression.
  • http://www.rethinkpbc.com/pbc-symptom-management/depression/ Depression | RethinkPBC.com - Depression in PBC may be related to fatigue, and may be severe enough to require treatment with antidepressants regardless of use of UDCA.

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  • Deanna R. Miller - This is very disappointing!

    This was one of two software selections that I bought my mother for her birthday. There is a known problem with the program yet it continues to be distributed and sold. You cannot load the fonts on the long version or the short version. Broderbund is aware of this problem and has done absolutely nothing to make it right. Amazon, shame on you for selling this.

  • rich super - so far so good

    I read a lot of the reviews and I purchased the cross bars for my 2014 jeep grand cherokee. I installed the the other day (took 10 minutes tops) I did read about the poor quality hardware however i didn't have a problem with it at all. (however i did use my own allen wrench and not the one supplied with the bars). today I drove into work about a 40 minute drive at highway speeds and not even a peep from the bars as far as a whistle goes. the supplied instructions were very vague, i read them after the install but if you have a little common sense and some mechanical skill you can easily install them without the instructions.

  • PowayBob - Buyers Beware. Mediocre product that comes with lots of SPAM.

    Mediocre product. Many free packages are superior. Also, once you register one of their products, you are bombarded with upgrade notices with only "24 hrs. to save". Several attempts to unsubscribe appear to be ignored, so I now forward them as SPAM. I've opted for an online option as a much preferred alternative. Buyers beware.

  • Travis Rohner - Very disappointed! My daughter was so excited to get this ...

    Very disappointed! My daughter was so excited to get this watch. She saved her money to buy herself. When we opened the box it looked like it had already been opened. When we plugged it in to charge the charger wouldn't work. It would fall out. So we used a charger we already had and plugged it into the computer. Someone else had already used it and returned it because their pictures were on it. Lovely, we got a used product that we paid full price for. Very upset that amazon would sell us a product that was used and defective. I've never posted a review before, but this one was too bad not to be know.

  • Constance P. Drescher - I like this product but do not know yet whether it ...

    I like this product but do not know yet whether it will be effective. Unfortunately (and this has nothing to do with the product itself}, the dispenser does not work so I am spilling a lot of shampoo every time I use it as I have to lift the dispenser out of the bottle.