www.cureline.com Review:

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Global human biospecimens biotech company and CRO - Cureline is a global human biospecimens biotech company providing effective solutions for scientific and clinical research projects. The company was founded by a group of scientists and biotech entrepreneurs, who established the human tissue biorepository for SUGEN (acquired by Pharmacia/ Pfizer) and contributed in the development the successful cancer therapy sunitinib Sutent® (Pfizer).

http://www.cureline.com/about-us.html About us | Cureline, Inc - Since 2003, Cureline, Inc. has been dedicated to innovation in human tissue research.

http://www.cureline.com/cureline-team.html Cureline Management Team | Olga Potapova, Kathleen Talmadge, Dmitry Belyaev, Olga Voronina - Cureline management team is well known and respected among members of the scientific community. We are committed to providing the highest quality consulting, project management and study support, which will help you to achieve your research program goals. Our clinical team includes a group of highly motivated and well trained medical doctors, medical assistants, lab techs, and general support members.

http://www.cureline.com/contact-cureline.html Cureline, Inc | Global Biobank and Human Biospecimen CRO - Address: 290 Utah Avenue - Suite 300 - South San Francisco, CA 94080. Phone 650.875.6400 ; Fax 650.875.6484. Email: [email protected]

http://www.cureline.com/human-biospecimen-acquisition.html Human Biospecimen Acquisition | Human Tissues for Research - Cureline, Inc - Cureline offers to the biopharmaceutical and diagnostics companies collection, preservation and processing of clinically-defined and consented human tissues for research. We have standard and custom tissue procurement protocols available for your research programs.

http://www.cureline.com/biorepository.html Biorepository | Global Biobank Cureline, Inc - Cureline procures, ships, stores, analyses and distributs thousands of human specimens every year. Our major biorepository is located in the United States and high-quality human specimens are immediately available to our clients and collaborators.

http://www.cureline.com/fresh-human-tissues-and-blood.html Fresh Human Tissues and Blood | Cureline, Inc - Cureline provides high-quality human specimens for biomedical research. Fresh human tissues and blood are available for our USA-based customers. Samples from healthy donors and clinically-defined patients are available in 24 - 48 hours after collection. AQIXRPMIHuman colon (30 hours, H&E stain)Since 2007, Cureline has adopted AQIX technology (www.aqix.com) for preservation and transportation of fresh human tissues.

http://www.cureline.com/matching-tumor-tissue-sets.html Matching Tumor Tissue Sets | Cureline, Inc - Cureline is a leading provider of primary tumor and matching recurrent or metastatic paired FFPE tumor samples. Such specimens are crucial for discovery of novel biomarkers of tumor progression and drug resistance.

http://www.cureline.com/primary-cell-lines.html Primary Cell Lines | Cureline, Inc - Cureline research team has adopted effective protocols for preparation of primary human cell lines from solid tumors, cancer blood, cancer bone marrow and normal tissues. The prepared primary cell cultures maintain their differential state and can be used as an in-vitro model system to study relevant disease changes and susceptibility to new drug candidates.

http://www.cureline.com/treatment-relevant-cancer-serum.html Treatment-Relevant Cancer Serum | Cureline, Inc - Cureline has established a collaboration to collect extensive serum sets from oncology patients. Samples are being collected throughout the course of a patient’s prescribed treatment plan. Currently our biorepository holds approximately fifteen thousand serum samples from over 1,500 patients with various cancer diagnoses.

http://www.cureline.com/human-therapeutic-plasma.html Human Therapeutic Plasma | Cureline, Inc - Cureline has established collaborations with multiple clinical sites for acquisition of human theraputic plasma in Oncology and Inflammatory diseases. Well-characterised marker-specific samples of human plasma are available from consented patietns for diagnostics development and validation. Matching normal controls also could be procured. More information will be available in April 2008.

http://www.cureline.com/human-ffpe-tissue-for-research.html Human FFPE Tissue for Research | Cureline, Inc - Collection Protocol Specifications: A piece of human tissue prepared by a certified medical pathologist is submerged in 10% neutral-buffered formalin for maximum of 24 hours and embedded in IHC-grade paraffin. The target FFPE specimen size is 0.5 x 1 x 1 cm, but it can vary significantly depending on the nature of the disease and tissue type.

http://www.cureline.com/frozen-human-tissue-for-research.html Frozen Human Tissue for Research | Cureline, Inc - Collection Protocol Specifications: Small pieces of tissue prepared by a certified medical pathologist are snap-frozen in liquid nitrogen usually within 20 - 30 min after the surgical excision or 4 - 12 hours postmortem in autopsy cases. A standard sample weighs 0.5 - 2 g on average and is supplied in a standard cryovial.

http://www.cureline.com/human-blood-and-bone-marrow.html Human Blood and Bone Marrow | Cureline, Inc - Whole blood is supplied as a 4 - 8 ml frozen blood sample in a standard K2-EDTA tube (the anti-coagulation agent can be changed per customer request). Serum/Plasma is obtained from 8 ml of whole blood using standard blood fraction separation procedures (e.g. BD Biosciences serum/plasma collection tubes and protocols). The specimens are supplied as snap-frozen aliquots (0.

http://www.cureline.com/cell-fractions-from-human-biospecimens.html Cell Fractions from Human Biospecimens | Cureline, Inc - Cureline rsquo;s research team has developed protocols for preparation of primary human viable cells and and snap-frozen cell pellets for in-vitro functional studies and protein and RNA expression analysis. Our scientists can prepare viable primary cells and frozen cell fractions from tumor and normal tissues, blood and bone marrow. If you would like to implement your custom protocol, please contact Cureline rsquo;s Scientific Director, Olga Potapova, Ph.

http://www.cureline.com/human-biospecimen-sets.html Human Biospecimen Sets | Cureline, Inc - Oncology - Solid Tumors, Hematological Malignancies, Rheumatoid Arthritis, Normal Human Brain Map, Normal Human Tissue Panel

http://www.cureline.com/therapeutic-areas.html Therapeutic Areas - Oncology, Inflammation, Infectious Diseases | Cureline, Inc - Cureline is the global service provider for biomarker research and diagnostic specimen collection in oncology (solid tumors, hematology), inflammation, infectious diseases, and other therapeutic areas.

http://www.cureline.com/human-tumor-tissues.html Human Tumor Tissues | Cureline, Inc - Since its inception, the primary focus area of our company has been oncology. Every year we expand our procurement network to include new clinical and research centers around the world in order to collect genetically-diverse human tumor specimens, including frozen tumor, tumor FFPE and matching blood products. Currently we manage human tumor tissue acquisition projects in Russia, Eastern Europe, India, the Philippines and the USA.

http://www.cureline.com/hematology-oncology-tissues.html Hematology Oncology Tissues | Cureline, Inc - Cureline collects biospecimens from patients with all types of hematologic malignancies (ALL, AML, CLL, CML, MM, MDS, etc.) in the chronic and crisis stages of the disease. Cancer blood, bone marrow aspirate and bone marrow trephine biopsy specimens obtained from these patients are used for cellular and molecular analyses for drug discovery, preclinical research, drug safely evaluation, biomarker development and pre-selection of indications for clinical trials.

http://www.cureline.com/biospecimens-inflammatory-diseases.html Biospecimens, Inflammatory Diseases | Cureline, Inc - Rheumatoid Arthritis (RA),a chronic autoimmune disorder causing joint inflammation and damage, is one of the most studied indications in recent years.

http://www.cureline.com/biospecimens-neurological-diseases.html Biospecimens, Neurological Diseases | Cureline, Inc - Cureline acquisition protocols for the collection of clinically-defined neurological specimens currently include the following conditions:Parkinson's DiseasePostmortem collection of S. nigra from patients diagnosed with Parkinson's disease

http://www.cureline.com/normal-human-tissue-for-research.html Normal Human Tissue for Research | Cureline, Inc - FDA policy In 1997, the Center for Biologics Evaluation and Research (a division of the Food and Drug Administration and the Department of Health and Human Services) published recommendations for the approval of monoclonal antibody products for medical use. Non-target specific binding to human tissue may have serious consequences when pharmacologically active antibodies (Ab) are used for treatment of disease.

http://www.cureline.com/infectious-diseases.html Infectious Diseases | Cureline, Inc - Curelne offers high quality biospecimens from patients with various infectious diseases: hepatitis, HIV, Tuberculosis, Sepsis, In-hospital pneumonia.

http://www.cureline.com/biospecimens-other-indications.html Biospecimens, Other Indications | Cureline, Inc - Cureline team works closely with principal investigators and project managers on developing custom protocols, conducting feasibility studies and managing biosample acquisition projects.

http://www.cureline.com/analytical-human-tissue-research-services.html Analytical Human Tissue Research Services | Cureline, Inc - Cureline provides human tissue for research in many therapeutic areas including solid tumor oncology, hematological malignancies, inflammatory diseases, neurological diseases

http://www.cureline.com/drug-sensitivity-in-3-d-histocultured-tumors.html Fresh Tumor Tissue Analysis | Cureline, Inc - Histocultures are three-dimensional tissue cultures that maintain in-vivo-like phenotype in contrast to monolayer cultures.

http://www.cureline.com/translational-histopathology.html Translational Histopathology | Cureline, Inc - For all human biospecimens provided by Cureline a detailed pathology report from a US-board certified medical pathologist and H&E slides are prepared upon request.

Country: 54.208.124.87, North America, US

City: -77.4728 Virginia, United States

Amazon Customer - Flabbergasted

That's the word of the day. I am FLABBERGASTED that this got such high ratings? Please don't read further if you don't want spoilers. I'll try to keep it to a minimum but it can't be helped.

Jimmy - i hate the little metal buckles

i hate the little metal buckles. i knew it was going to be an issue going in, but i really liked everything else about the bag. i don't want to use the velcro because over time the loop half starts to fray. the bag doesn't hold much integrity when using the handle and the handle feels more like an afterthought. overall i like the bag, but it needs some improvements with the handle and that damn buckle! also the water bottle holder is too small! it's good for a small plastic water bottle, but it barely holds my metal water bottle. it should be a deeper, a net, elastic band and a cinch so it can be adjusted to various diameters.

Terrell Welch - Pretty Good

Autodesk Sketchbook is pretty good. I am enjoying the quality of work it allows me to produce. I have been used to Photoshop Elements and this is a major change from that. You have less control over the details that you can choose when compared to Elements. But, you can do work from scratch on Autodesk Sketchbbok. The lines are, indeed, smooth, and you have a decent selection to choose from. Although I have to get used to the technical aspects that differ and make the software have less ease of use than elements, the program is still pretty good. And I am glad I bought it. When comparing the two programs, for the price, Sketchbook is a lot better.